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Individuals who have developed allergic reactions from aspirin or other NSAIDs may experience an allergic reaction to Celecoxib and should not take Celecoxib. The dose usually is 100 mg twice daily or 200 mg as a single dose. Celecoxib is used for the relief of acute pain and the pain of menstrual cramps. Fluconazole increases the concentration of Celecoxib in the liver. Before using this medication, tell your doctor or pharmacist if you are allergic to it or to sulfa drugs. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. It as instructed by your doctor. Before using this medication, tell your doctor or pharmacist your medical history, especially of blood flow problem in the brain. If you are allergic to it or to sulfa drugs.