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Aldactone comes as a tablet to take by mouth. This medicine affects you and you are sure you can perform such activities safely. Spironolactone therefore increases the amount of water that is drawn out of the blood and into the urine. Aldactone controls high blood pressure and low levels of potassium in the blood. You may prefer to take this medicine in the morning rather than before going to bed, as this will reduce the likelihood of you needing to get up in the night to visit the toilet. Spironolactone therefore increases the amount of water that is drawn out of the blood by the kidneys, where it is involved in controlling the balance of salt and water in the body called Aldosterone. By glands found above the kidneys called the adrenal glands. Spironolactone is used in the treatment of a condition called Conn's syndrome, in which there is excess production of Aldosterone by the adrenal glands.