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Inderal is usually used in combination with clonidine to lower blood pressure, there is a risk of a rebound increase in blood pressure if the clonidine is stopped. In the published literature describe cases in which Propranolol was used as a suicide agent. There may be increased difficulty in treating an allergic type reaction in patients on beta-blockers. The heart's need for oxygen, which means it can also be used in the management of angina. Beta-blockers. Beta-blockers work by blocking beta receptors that are found in various parts of the body. Propranolol may increase oxygen requirements by increasing left ventricular fiber length, end diastolic pressure, and the velocity and extent of myocardial contraction. There may be increased difficulty in treating an allergic type reaction in patients on beta-blockers.
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